Contribution of immunology to build precision medicine in reproduction: present and future

نویسندگان

چکیده

Infertility affects millions of people reproductive age. The failure a blastocyst to implant is leading cause psychological distress. It became increasingly evident that an effective immune dialogue occurs at each step in the fluids surrounding oocyte, spermatozoa, embryo, or endometrium. Exploring and deciphering this could potentially help understand why 50% healthy euploid blastocysts fail implant. Introducing immunology into medicine requires change mindset bring hypothesis clinical applications. Implantation embryo prepared uterus order with which able express repair itself. uterine profile patients previous implantation failures (IF) recurrent miscarriages (RM) has already been developed under evaluation as precision tool equilibrate environment before increase subsequent live birth rate after transfer. Immunology may also be fundamental future identify through non-invasive procedure competence oocytes embryos reliable biomarkers quantified follicular supernatants during vitro fertilization (IVF) process. Non-invasive would allow physicians competent based on their ability communicate mother energetic potential for all self-repair processes should occur preimplantation period. This area research only beginning.

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ژورنال

عنوان ژورنال: Exploration of immunology

سال: 2022

ISSN: ['2768-6655']

DOI: https://doi.org/10.37349/ei.2022.00067